CORRELATION OF RED-CELL DISTRIBUTION WIDTH (RDW) IN FIRST DAY AND FOURTH DAY BASED ON CURB-65 SCORES AND PSI SCORES IN PNEUMONIA COMMUNITY PATIENTS

Abstract

Introduction: RDW (Red-cell Distribution Width) is a concept of variations in the size of red blood cells and reflects the heterogeneity of the volume of red blood cells. RDW is a component of the complete count (Complete Blood Count / CBC). Until now, the clinical significance of RDW has been limited to the differential diagnosis of anemia. However, recent reports linking increased of RDW can predict severe mortality and morbidity in cardiovascular disease, pneumonia, rheumatoid arthritis, colon cancer and metabolic syndrome. PSI and CURB-65 were used in assessing disease severity and predicting the prognosis of pneumonia patients using PSI and CURB-65 Aim: To investigate the RDW value as a prognostic marker for the death of community pneumonia patients through PSI and CURB-65 scores

Methods: Cohort study was conducted at the Haji Adam Malik General Hospital in Medan from June 2018 to March 2019 with total sample are 50 pneumonia patients. Patients performed RDW examinations on the first and fourth days, sputum cultures, and calculation of PSI and CURB-65 scores. Data analysis using SPSS 22nd.

Result: 50 pneumonia patients were tested for RDW on the first and fourth days with a median result are 13.65% and 14.70%. There is a positive correlation of the fourth day RDW to CURB 65 with moderate correlation (p = 0.001; r = 0.441), but no correlation of the fourth day RDW to PSI (p=0,178). This study assess the difference of RDW for life status patient. It was found that there were differences in the fourth day RDW which was statistically significant for the patient's life status (p = 0.046).

Conclusion: RDW on the fourth day is significantly corelated to CURB 65 scores