DIFFERENCES IN LIPID PROFILES LEVELS BETWEEN MIGRAINE PATIENTS AND TENSION TYPE HEADACHE

Abstract

Background: Headache is one the most common neurologic disorders. Various mechanism have been proposed as the pathogenesis of headache. Recently evidences have supported that lipid profiles might play a role in headache.

Methods: a cross-sectional study was performed on 62 patients migraine and TTH , aged ≥ 18 years. Diagnosis was made based on The V National Consensus of Indonesian Neurologist Association Headache Study Group. Venous blood samples were obtained from eligible subjects. Laboratory measurements of standard biochemical parameters were performed on computerized laboratory analyzers.

Results: The mean levels of total cholesterol and triglyceride significantly higher in migraine groups when compared to TTH group (P < 0.001). LDL was significantly higher in migraine groups than in TTH group (P = 0.001). Furthermore, mean HDL was not significantly different in those groups (P = 0.437). All of the lipid profile did not show a significant relationship with the intensity of headache (p > 0.05).

Conclusion: Total blood cholesterol, triglyceride, and LDL were higher in migraine patients than TTH patients. There is no significant different of HDL in both groups.