CORRELATION OF DEPRESSION LEVEL WITH LIPID PROFILE IN REGULAR HEMODIALYSIS CRONIC KIDNEY DISEASE PATIENTS

Abstract

Introduction : Depression is widely recognized as the most common psychiatric problem in chronic kidney disease patients undergoing hemodialysis. Depression causes an increase of glucocorticoids and catecholamines hormones, resulting in impaired lipid metabolism.

Aim : This study aims to determine the correlation between depression level and lipid profile in chronic kidney disease patients undergoing hemodialysis.

Methods : This study is a cross sectional study involving 30 respondents at Haji Adam Malik Hospital Medan for the period October – November 2019. Respondents were assessed for their level of depression using the BDI (Beck Depression Inventory) and laboratory examination of total cholesterol, HDL, LDL, and triglycerides.

Results : Of all study subjects, 13 respondents (43.3%) had mild depression, 11 (36.7%) had moderate depression, and 6 (20%) had severe depression. Bivariate analysis found significant relationship between the level of depression and triglyceride levels (p = 0.046).

Conclusion : The more severe degree of depression, the triglyceride levels will tend to increase in patients with chronic kidney disease undergoing hemodialysis.