SYNTAX II SCORE AS A PREDICTOR OF MAJOR ADVERSE CARDIOVASCULAR EVENTS (MACE) IN PATIENTS UNDERGOING CORONARY ARTERY BYPASS SURGERY (CABG) DURING TREATMENT AT HAJI ADAM MALIK HOSPITAL (RSUP HAM) MEDAN

Abstract

Background: Acute Coronary Syndrome is still the main cause of death in Indonesia with a mortality rate of 384.9 per 100,000 population. Syntax score is a risk stratification modality for patients undergoing revascularization and can predict mortality and morbidity rates. Objective: Assessing the accuracy of Syntax II Score in predicting Major Adverse Cardiovascular Events (MACE) in patients undergoing CABG.

Methods: ACS patients who underwent CABG at Haji Adam Malik Hospital Medan in August 2019, which was observed for MACE that occurred during in-hospital treatment. The sample who experienced MACE will be assessed for Syntax scores II which are grouped into 2 groups, moderate Syntax scores (<32) and high Syntax scores (≥ 33). ROC curve analysis will get the cut-off point.

Results: From 60 subjects, 10 patients (16.7%) experienced MACE. ROC curve analysis showed that the Syntax II Score was able to predict the incidence of Total MACE with cut-off points was 29.85 (AUC=0.869, p<0.001, sensitivity 90%, specificity 68%) and cut-off point for Heart failure was 37.05 (AUC) = 0.935, p=0.004, sensitivity 75%, specificity 83.9%).

Conclusion: Syntax II Score can be used as a valid scoring system to predict the incidence of MACE in ACS patients who underwent CABG