CORRELATION OF BECK DEPRESSION INVENTORY II (BDI II) SCORE AND VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF) LEVELS IN TYPE 2 DIABETES MELITUS PATIENTS

Abstract

Introduction: Depression defined as feelings of sadness, disappointment, hopelessness, and loss of interest in life. Depression can be assessed by Beck Depression Inventory II (BDI II) questionnaire. Type 2 Diabetes mellitus (DM) is a chronic metabolic disorder due to insulin defisiency or insulin resistence. Prevalence of depression has increased two times in type 2 diabetes mellitus patients. Vascular Endothelial Growth Factor (VEGF) was a vascular permeability and angiogenesis factor. Depression and Type 2 Diabetes Mellitus would increase VEGF.

Method: It was a correlative analytic cross sectional study, in November 2019 on Type 2 DM patients whose BDI II score and VEGF levels were assessed in outpatient clinic of Haji Adam Malik General Hospital Medan. Data were analyzed by SPSS.

Results: There was a very strong correlation of BDI II scores and VEGF levels (p = 0.0001). There was correlation between hemoglobin and age, fasting blood glucose levels and 2 hours after eating blood glucose levels, 2 hours after eating glucose levels and HbA1C (p = 0.0001, p = 0.0001, p = 0.0001)

Conclusion: There was a very strong positive correlation of BDI II Scores and VEGF levels in Type 2 Diabetes Mellitus patients.