THE ROLE OF CD4 LEVELS IN PREDICTING PENICILLIOSIS IN HIV/AIDS PATIENTS AT HAJI ADAM MALIK GENERAL HOSPITAL MEDAN

Authors

  • Epifania Yoan Theresa Ginting, Tambar Kembaren, Endang, Dian Dwi Wahyuni & Putri C. Eyanoer

Keywords:

Penicilliosis, HIV, AIDS, biopsy

Abstract

Introduction: Around 36.9 million people currently live with HIV with a high number of deaths, which can threaten the lives of HIV sufferers not only from the virus itself, but also opportunistic infections (OIs). Penicillium marneffei is one of the OIs that causes morbidity and mortality in patients infected with HIV. In areas with high endemicity, a CD4 level <100 cells/µL is predominantly at risk of infection with P. Marneffei.

Aim: To know the role of levels CD4 <100 cells/µL in predicting the occurrence of penicilliosis HIV/AIDS patients.

Methods: Diagnostic test study with cross-sectional design on 100 respondents, where research data uses secondary data within medical records of HIV/AIDS patients to get cut off value, sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and accuracy of CD4 <100 cells /µL for diagnose the penicillosis. Data analysis using SPSS 20th.

Result: Based on the results of diagnostic tests CD4 levels <100 cells/µL with the incidence of penicilliosis in HIVAIDS patients, this study get a cutoff value: 14.5 cells/µL with [AUC: 0.5, p = 0.806; Sensitivity (63.1%); Specificity (42.9%); PPV (67.2%); NPV (38.5%); Accuracy (56%)].

Conclusion: In this study, CD4 <100cells/µL can not be used to predict penicilliosis in HIV/AIDS patients

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Published

2020-01-15

How to Cite

Epifania Yoan Theresa Ginting, Tambar Kembaren, Endang, Dian Dwi Wahyuni & Putri C. Eyanoer. (2020). THE ROLE OF CD4 LEVELS IN PREDICTING PENICILLIOSIS IN HIV/AIDS PATIENTS AT HAJI ADAM MALIK GENERAL HOSPITAL MEDAN. International Journal of Research Science and Management, 7(1), 47–53. Retrieved from http://ijrsm.com/index.php/journal-ijrsm/article/view/65

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