RELATIONSHIP BETWEEN NEUTROPHYL-TO-LYMPHOCYTE RATIO WITH CORONARY ARTERY LESION IN ACUTE CORONARY SYNDROME PATIENTS

Abstract

Acute Coronary Syndrome (ACS) is the leading cause of death from cardiovascular disease. ACS is an abnormal condition caused by cardiac dysfunction and narrowing of the coronary arteries. Narrowing of the coronary arteries in the pathophysiology of ACS involves the process of atherosclerosis. It is important to assess early whether there are coronary artery lesions or not. Neutrophyl-to-lymphocyte Ratio (NLR) is a simple ratio between neutrophils and lymphocytes that can be obtained from routine blood tests and is known to be related to the severity of coronary artery lesions. This research is a retrospective research on 61 samples obtained through consecutive sampling between January-December 2018 at H. Adam Malik General Hospital, Medan. Data obtained from medical records of patients where NLR levels were found from routine blood results and the number of coronary artery lesions found from the results of the patient's coronary angiography. All data were collected and analyzed using SPSS version 22. Based on data analysis, we found that there’s a significant relationship between NLR levels and the number of coronary artery lesions in ACS patients with p = 0.002